NCT07455656 Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction
| NCT ID | NCT07455656 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Al-Azhar University |
| Condition | Malocclusions |
| Study Type | INTERVENTIONAL |
| Enrollment | 16 participants |
| Start Date | 2025-08-01 |
| Primary Completion | 2026-08-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 16 participants in total. It began in 2025-08-01 with a primary completion date of 2026-08-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S. T. Varughese, et al. (2019) , "Effect of vitamin D on canine distalization and alveolar bone density using multi-slice spiral CT: a randomized controlled trial
Eligibility Criteria
Inclusion criteria: 1. Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and bimaxillary protrusion). 2. Fully erupted permanent teeth (except third molar). 3. Age 13-20 patients. 4. No previous orthodontic treatment. 5. Good oral and general health. 6. No systemic disease or regular medication that could interfere with and/or affect orthodontic teeth movement. Exclusion criteria: 1. Patients with impacted canines. 2. Patients with severe crowding. 3. Patients with untreated decay or any endodontic lesions. 4. Patients with thyroid, parathyroid, or renal and liver disease.
Contact & Investigator
Dr. Ramadan Yusuf Abu-Shahba Y Dr. Ramadan Yusuf Abu-Shahba, PhD
STUDY DIRECTOR
rmadanyusf@azhar.edu.eg
Frequently Asked Questions
Who can join the NCT07455656 clinical trial?
This trial is open to participants of all sexes, aged 13 Years or older, up to 20 Years, studying Malocclusions. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07455656 currently recruiting?
Yes, NCT07455656 is actively recruiting participants. Contact the research team at mahmoud_elsaid@azhar.edu.eg for enrollment information.
Where is the NCT07455656 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT07455656 clinical trial?
NCT07455656 is sponsored by Al-Azhar University. The principal investigator is Dr. Ramadan Yusuf Abu-Shahba Y Dr. Ramadan Yusuf Abu-Shahba, PhD at rmadanyusf@azhar.edu.eg. The trial plans to enroll 16 participants.