NCT07577700 Assessment of Pulmonary Perfusion and Hemodynamic Measurements by Electrical Impedance Tomography in Patients Undergoing Pulmonary Thromboendarterectomy.
| NCT ID | NCT07577700 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Sao Paulo General Hospital |
| Condition | Pulmonary Thromboendarterectomy |
| Study Type | INTERVENTIONAL |
| Enrollment | 36 participants |
| Start Date | 2025-02-25 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 36 participants in total. It began in 2025-02-25 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Chronic thromboembolic pulmonary hypertension (CTEPH) is a condition in which old blood clots block the blood vessels in the lungs, making it harder for the heart to pump blood through the lungs. Surgery called pulmonary thromboendarterectomy can remove these clots and improve blood flow, but doctors need reliable ways to evaluate lung blood flow before and after surgery. This study will evaluate a bedside imaging method called electrical impedance tomography (EIT), which can measure how blood flows through different regions of the lungs without radiation or invasive procedures. Patients undergoing surgery for CTEPH will be monitored with EIT before and after surgery, and the results will be compared with standard lung perfusion imaging. The goal of this study is to determine whether EIT can provide useful information about lung blood flow and changes after surgery, and whether it could serve as a complementary bedside tool to help monitor patients with CTEPH.
Eligibility Criteria
Inclusion Criteria: \- Patients diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) followed at the Pulmonology Service of InCor-HCFMUSP and scheduled for pulmonary thromboendarterectomy at InCor-FMUSP. Exclusion Criteria: * Age under 18 years * Pregnancy * Structural heart disease (atrial septal defect, ventricular septal defect, or valvular heart disease) * Cardiac arrhythmias * Use of a cardiac pacemaker or other implantable electronic device * Skin lesions on the thoracic region at the site of EIT electrode belt placement * Absence of central venous access on the day of the preoperative protocol evaluation * Difficulty understanding the procedures to be performed * Refusal to participate in the study (non-signing of the Informed Consent Form) * Refusal by the attending medical team
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07577700 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Pulmonary Thromboendarterectomy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07577700 currently recruiting?
Yes, NCT07577700 is actively recruiting participants. Contact the research team at marcelo.amato@hc.fm.usp.br for enrollment information.
Where is the NCT07577700 trial being conducted?
This trial is being conducted at São Paulo, Brazil.
Who is sponsoring the NCT07577700 clinical trial?
NCT07577700 is sponsored by University of Sao Paulo General Hospital. The trial plans to enroll 36 participants.