NCT06012227 Assessment Metabolic Flexibility in Middle-aged Individuals: The Nutritional Impact of Cheese Consumption
| NCT ID | NCT06012227 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Cagliari |
| Condition | Metabolism |
| Study Type | INTERVENTIONAL |
| Enrollment | 105 participants |
| Start Date | 2022-01-20 |
| Primary Completion | 2023-07-27 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 105 participants in total. It began in 2022-01-20 with a primary completion date of 2023-07-27.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of the study will be to evaluate the impact of consumption of meat and dairy products from extensive or intensive farming on apparently healthy individuals aged between 45 and 65 years, a stage of life associated with reduced metabolic flexibility and changes in lipid metabolism. The study will analyze: 1. The transcription factor PPAR-α determined by the gene expression of PPAR-α in white blood cells, variations in circulating fatty acid metabolism, and the endocannabinoid system determined by circulating analysis of N-acylethanolamine (NAE), and 2-monoacylglycerols (2-MG); 2. Metabolic flexibility, determined by indirect calorimetry in fasting condition during an incremental exercise; 3. Body composition, determined by bioimpedance analysis, waist circumference, and waist-to-hip ratio.
Eligibility Criteria
Inclusion Criteria: * 45-65 years of age * BMI \< 27 * waist-to-hip ratio female\<0.85; male \< 0.98 Exclusion Criteria: * metabolic diseases * Physical activity of competitive nature * Vegans and vegetarians * Intolerances and allergies to the foods under study
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06012227 clinical trial?
This trial is open to participants of all sexes, aged 45 Years or older, up to 65 Years, studying Metabolism. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06012227 currently recruiting?
Yes, NCT06012227 is actively recruiting participants. Contact the research team at banni@unica.it for enrollment information.
Where is the NCT06012227 trial being conducted?
This trial is being conducted at Monserrato, Italy.
Who is sponsoring the NCT06012227 clinical trial?
NCT06012227 is sponsored by University of Cagliari. The trial plans to enroll 105 participants.