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Recruiting NCT07487961

Assess Abdominal Aortic Diameter in Females

Trial Parameters

Condition Aorta Disease
Sponsor Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Study Type OBSERVATIONAL
Phase N/A
Enrollment 652
Sex FEMALE
Min Age 50 Years
Max Age N/A
Start Date 2025-09-29
Completion 2027-07-30

Brief Summary

Female subjects aged 50 years or older will be enrolled. Biometric data (measurements) of the aorta and iliac vessels, demographic data, pathophysiological history, and data relating to menarche, pregnancy/infertility, and menopause will be collected. The aortic diameter measurement protocol will follow standard clinical practice. Measurements will be performed by placing the probe on an axis perpendicular to the aortic axis, manually positioning the calipers in the antero-posterior and lateral-lateral directions, recording both the outer-to-outer (OTO) and inner-to-inner (ITI) diameters. Additionally, the presence of thrombus and/or calcifications and the outer-to-outer (OTO) measurement of the common iliac arteries will be detected. Primary objective: Definition of the ultrasound diameter of the abdominal aorta in the female population. Secondary objective: Identification of any sex-specific risk factors associated with abdominal aortic disease (aneurysm) in the female population. Secondary objective: Identification of any sex-specific risk factors associated with abdominal aortic disease (atherosclerosis) in the female population.

Eligibility Criteria

Inclusion Criteria: * female sex * ≥ 50 YO Exclusion Criteria: * \< 50 years * Previous diagnosis of abdominal/thoracic aneurysm disease * Subjects who have previously undergone surgery (both open and endovascular) on the thoracic and/or abdominal aorta * Presence of mental disability and/or inability to sign informed consent

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