NCT07486271 Artificial Intelligence in Aortic Regurgitation
| NCT ID | NCT07486271 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chinese University of Hong Kong |
| Condition | Aortic Regurgitation Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 540 participants |
| Start Date | 2025-12-01 |
| Primary Completion | 2028-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 540 participants in total. It began in 2025-12-01 with a primary completion date of 2028-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This research project aims to develop and validate a tool that uses artificial intelligence (AI) to automatically detect and quantify aortic regurgitation (AR). The clinical efficacy of this tool will be established by comparing it to manual diagnostic methods in a multicenter randomized controlled trial. By leveraging deep learning (DL) techniques, the AI system will automate aortic regurgitation (AR) detection, measurement, and diagnosis, addressing challenges like variability in echocardiographic interpretations and the need for specialized expertise. It will integrate multiple echocardiographic parameters to provide accurate, standardized, and efficient AR diagnoses, reducing human error and improving consistency. This tool will enhance diagnostic precision and accessibility, improving clinical outcomes and extending advanced diagnostic capabilities to a broader range of healthcare environments, including resource-limited settings.
Eligibility Criteria
Inclusion Criteria: * Confirmed AR diagnosis via TTE and Doppler imaging per guidelines. * Age ≥ 18 years. * Adequate acoustic window for AR quantification. Exclusion Criteria: * Prior cardiac transplant or implanted cardiac devices. * Poor image quality. * Pregnancy or lactation.
Contact & Investigator
Alex PW Lee, Professor
PRINCIPAL INVESTIGATOR
Chinese University of Hong Kong
Frequently Asked Questions
Who can join the NCT07486271 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Aortic Regurgitation Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07486271 currently recruiting?
Yes, NCT07486271 is actively recruiting participants. Contact the research team at xueting@cuhk.edu.hk for enrollment information.
Where is the NCT07486271 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT07486271 clinical trial?
NCT07486271 is sponsored by Chinese University of Hong Kong. The principal investigator is Alex PW Lee, Professor at Chinese University of Hong Kong. The trial plans to enroll 540 participants.