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Recruiting NCT05139797

Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)

Trial Parameters

Condition Cardiac Amyloidosis
Sponsor Cedars-Sinai Medical Center
Study Type OBSERVATIONAL
Phase N/A
Enrollment 300
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2021-11-18
Completion 2026-01-01
Interventions
EchoNet-LVH screening for cardiac amyloidosis

Brief Summary

Despite rapidly advancing developments in targeted therapeutics and genetic sequencing, persistent limits in the accuracy and throughput of clinical phenotyping has led to a widening gap between the potential and the actual benefits realized by precision medicine. Recent advances in machine learning and image processing techniques have shown that machine learning models can identify features unrecognized by human experts and more precisely/accurately assess common measurements made in clinical practice. The investigators have developed an algorithm, termed EchoNet-LVH, to identify cardiac hypertrophy and identify patients who would benefit from additional screening for cardiac amyloidosis and will prospectively evaluate its accuracy in identifying patients whom would benefit from additional screening for cardiac amyloidosis.

Eligibility Criteria

Inclusion Criteria: * Patients who have a high suspicion for cardiac amyloidosis by AI algorithm Exclusion Criteria: * Patients who decline to be seen at specialty clinic * Patients who have passed away

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