NCT06425406 Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial
| NCT ID | NCT06425406 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Henan Provincial People's Hospital |
| Condition | High-flow Nasal Cannula |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2024-06-15 |
| Primary Completion | 2025-11-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2024-06-15 with a primary completion date of 2025-11-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Compared with adults, children have higher metabolic needs, and the airway is more likely to collapse. Before tracheal intubation after anesthesia induction, the patient 's spontaneous breathing completely disappears. At this critical stage, the residual oxygen of the lung is consumed, resulting in hypoxemia and atelectasis. Therefore, it is necessary to explore the best oxygenation strategy during intubation. In addition, ultrasound has become a common equipment in the operating room. It has the advantages of portability, repeatability, and no radiation, and can provide strong support for the diagnosis of gastric distension.
Eligibility Criteria
Inclusion Criteria: * Age 2-10 years old; * American Society of Anesthesiologists (ASA) Level I or II; * Children with healthy lungs and hearts; * Clear headed and able to cooperate with anesthesiologists for treatment. Exclusion Criteria: * Contraindications for HFNC: (1) Complete obstruction of the upper respiratory tract; (2) Skull base fracture or nasal bone fracture; (3) Patients who refuse to use HFNC; * The American Society of Anesthesiologists (ASA) rating is greater than Level II; * Children with upper respiratory tract infections within 2 weeks; * Pulmonary dysfunction, congenital heart disease in children;
Contact & Investigator
Jun Zhou, PHD
STUDY CHAIR
Henan Provincial People's Hospital
Frequently Asked Questions
Who can join the NCT06425406 clinical trial?
This trial is open to participants of all sexes, aged 2 Years or older, up to 10 Years, studying High-flow Nasal Cannula. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06425406 currently recruiting?
Yes, NCT06425406 is actively recruiting participants. Contact the research team at 844523078@qq.com for enrollment information.
Where is the NCT06425406 trial being conducted?
This trial is being conducted at Zhengzhou, China.
Who is sponsoring the NCT06425406 clinical trial?
NCT06425406 is sponsored by Henan Provincial People's Hospital. The principal investigator is Jun Zhou, PHD at Henan Provincial People's Hospital. The trial plans to enroll 48 participants.