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Recruiting EARLY_Phase 1 NCT03384537

NCT03384537 Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash

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Clinical Trial Summary
NCT ID NCT03384537
Status Recruiting
Phase EARLY_Phase 1
Sponsor Cairo University
Condition Dental Diseases
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2024-02-08
Primary Completion 2026-10

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 45 Years
Study Type INTERVENTIONAL
Interventions
Listerine total care zeroChlorhexidine Mouthwash (0.2%).

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 1 is the earliest stage of human testing — safety and dosage are the primary focus. Visits are frequent and medical supervision is intensive. You will be among the first people to receive this treatment.

This trial targets 30 participants in total. It began in 2024-02-08 with a primary completion date of 2026-10.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The objective of this study is to compare the effect of Tropolone containing mouthwash versus CHX 0.2% mouthwash in reducing intraoral microorganism. Randomized clinical trial study

Eligibility Criteria

Inclusion Criteria: 1. Patients should be between 18- 45 years of age. 2. All the volunteers participated in this study will be healthy looking with free medical history. 3. The volunteers will be asked to suspend their usual oral hygiene practice from two to four days before experiment studying. Exclusion Criteria: 1. Patients with a compromised medical condition. 2. Volunteers that receive any antimicrobial agent during at least two weeks prior to study. 3. Volunteer with fixed, removable prosthesis or orthodontics appliance. 4. Volunteers with DMF above six will be excluded.

Contact & Investigator

Central Contact

Mohamed Abdelkadir, master

✉ mohamed.awad@dentistry.cu.edu.eg

📞 +201117147699

Principal Investigator

Abdelkadir

PRINCIPAL INVESTIGATOR

Study Principal Investigator

Frequently Asked Questions

Who can join the NCT03384537 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 45 Years, studying Dental Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT03384537 trial and what does that mean for participants?

Phase 1 trials are the first stage of human testing. The primary goal is to assess safety and determine appropriate dosage levels. Participants are closely monitored. These trials typically involve a small number of volunteers.

Is NCT03384537 currently recruiting?

Yes, NCT03384537 is actively recruiting participants. Contact the research team at mohamed.awad@dentistry.cu.edu.eg for enrollment information.

Where is the NCT03384537 trial being conducted?

This trial is being conducted at Cairo, Egypt.

Who is sponsoring the NCT03384537 clinical trial?

NCT03384537 is sponsored by Cairo University. The principal investigator is Abdelkadir at Study Principal Investigator. The trial plans to enroll 30 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology