NCT07476222 Anthropometric, Functional and Lifestyle Factors Associated With Testosterone Levels in Middle-Aged Men
| NCT ID | NCT07476222 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Andijan State Medical Institute |
| Condition | Testosterone Deficiency |
| Study Type | OBSERVATIONAL |
| Enrollment | 600 participants |
| Start Date | 2026-06-01 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 600 participants in total. It began in 2026-06-01 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Decreased testosterone levels in middle-aged men are associated with multiple metabolic, functional and psychosocial consequences. Early identification of modifiable factors associated with reduced testosterone levels may facilitate the early identification of men at increased risk of testosterone deficiency and support preventive healthcare strategies. This population-based cross-sectional observational study aims to investigate anthropometric, functional and lifestyle-related factors associated with serum total testosterone levels in middle-aged men. Approximately 600 men aged 35-59 years residing in the Andijan region of Uzbekistan will be recruited. Participants will undergo comprehensive assessment including anthropometric measurements, functional performance tests, standardised questionnaires and laboratory determination of serum total testosterone concentrations. Anthropometric variables will include body mass index, waist circumference, hip circumference, waist-to-hip ratio and waist-to-height ratio. Functional status will be assessed using hand-grip strength, the five-times chair-stand test and the 4-m walk test. Lifestyle-related factors will be assessed using standardised and study-specific questionnaires. Physical activity will be assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), while dietary habits, sleep characteristics, smoking status, alcohol consumption and psychosocial characteristics will be assessed using a structured study questionnaire. The study aims to identify factors associated with serum total testosterone levels and to develop a predictive model for the early identification of men at increased risk of testosterone deficiency.
Eligibility Criteria
Inclusion Criteria: * Men aged 35-59 years * Permanent residence in the Andijan region of Uzbekistan * Ability and willingness to provide written informed consent * Willingness to undergo clinical, anthropometric, functional and laboratory assessments Exclusion Criteria: * Previously diagnosed hypogonadism requiring testosterone replacement therapy * Current use of testosterone preparations or other medications known to substantially affect androgen status * Severe cardiovascular, hepatic or renal disease in the stage of decompensation * Clinically significant urological pathology * Severe psychiatric illness or cognitive impairment limiting study participation * Acute infectious or inflammatory conditions at the time of assessment
Contact & Investigator
Abdukhalim Kh. Abdurakhimov, PhD
PRINCIPAL INVESTIGATOR
Andijan State Medical Institute
Frequently Asked Questions
Who can join the NCT07476222 clinical trial?
This trial is open to male participants only, aged 35 Years or older, up to 59 Years, studying Testosterone Deficiency. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07476222 currently recruiting?
Yes, NCT07476222 is actively recruiting participants. Contact the research team at abduhalim@adti.uz for enrollment information.
Where is the NCT07476222 trial being conducted?
This trial is being conducted at Andijan, Uzbekistan.
Who is sponsoring the NCT07476222 clinical trial?
NCT07476222 is sponsored by Andijan State Medical Institute. The principal investigator is Abdukhalim Kh. Abdurakhimov, PhD at Andijan State Medical Institute. The trial plans to enroll 600 participants.