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Recruiting NCT03427736

NCT03427736 Anesthetics and Analgesics in Children

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Clinical Trial Summary
NCT ID NCT03427736
Status Recruiting
Phase
Sponsor Chi Dang Hornik
Condition Anesthesia
Study Type OBSERVATIONAL
Enrollment 551 participants
Start Date 2018-12-13
Primary Completion 2027-08-30

Eligibility & Interventions

Sex All sexes
Min Age 0 Years
Max Age 17 Years
Study Type OBSERVATIONAL
All Conditions
Interventions
Ketorolac TromethamineHydromorphoneKetamine

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 551 participants in total. It began in 2018-12-13 with a primary completion date of 2027-08-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.

Eligibility Criteria

Inclusion Criteria: 1. 0 to \<18 years of age at time of enrollment (must see applicable appendix for details as not all appendices enroll across the entire age range) 2. Parent and/or participant (if applicable) is able to understand the consent process and provides informed consent and HIPAA Authorization (if applicable) 3. Participant provides assent as required by the institutional review board (IRB) or research ethics board (REB) 4. Receiving one or more drugs of interest (DOI) per local standard of care 5. Meeting DOI-specific inclusion criteria (See Appendices) Exclusion Criteria: 1. Known pregnancy 2. Extracorporeal life support (i.e., ECMO, dialysis, ventricular assist device) 3. Any condition which would make the participant, in the opinion of the investigator, unsuitable for the study

Contact & Investigator

Central Contact

Kady-Ann Steen-Burrell, PhD

✉ kady.ann.steen.burrell@duke.edu

📞 919-530-9711

Principal Investigator

Chi Hornik, PharmD

PRINCIPAL INVESTIGATOR

Duke Clinical Research Institute

Frequently Asked Questions

Who can join the NCT03427736 clinical trial?

This trial is open to participants of all sexes, aged 0 Years or older, up to 17 Years, studying Anesthesia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03427736 currently recruiting?

Yes, NCT03427736 is actively recruiting participants. Contact the research team at kady.ann.steen.burrell@duke.edu for enrollment information.

Where is the NCT03427736 trial being conducted?

This trial is being conducted at Stanford, United States, Aurora, United States, Wilmington, United States, Chicago, United States and 9 additional locations.

Who is sponsoring the NCT03427736 clinical trial?

NCT03427736 is sponsored by Chi Dang Hornik. The principal investigator is Chi Hornik, PharmD at Duke Clinical Research Institute. The trial plans to enroll 551 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology