NCT06957509 Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment
| NCT ID | NCT06957509 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Karolinska Institutet |
| Condition | Early Childhood Caries (ECC) |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-04-04 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2025-04-04 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for caries risk. The main question to answer is: • Can the host´s salivary protein profile (expression and abundance) show a correlation with the caries prevalence between the individuals in the different study cohorts? Two cohorts of children with different documented demographic characteristics in the region of Stockholm (Sweden) will be examined. Participants will be asked to provide saliva samples and undergo clinical oral examinations conducted by trained dental practitioners.
Eligibility Criteria
Inclusion Criteria: * 3-year-old children residing in the areas served by Folktandvården Danderyd and Järva, respectively * Written consent, signed by both parents (guardians) Exclusion Criteria: * children older than three years * medication intake, and antibiotic use at the time of examination * children who have consumed food, drink, or used oral hygiene products within 2 hours before the dental visit * children who appear uncooperative during saliva sampling
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06957509 clinical trial?
This trial is open to participants of all sexes, aged 3 Years or older, up to 3 Years, studying Early Childhood Caries (ECC). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06957509 currently recruiting?
Yes, NCT06957509 is actively recruiting participants. Contact the research team at franziska.hetrodt@ki.se for enrollment information.
Where is the NCT06957509 trial being conducted?
This trial is being conducted at Stockholm, Sweden.
Who is sponsoring the NCT06957509 clinical trial?
NCT06957509 is sponsored by Karolinska Institutet. The trial plans to enroll 100 participants.