NCT06400901 Analysis of Deep Brain Nuclei LFP and Cortical EEG Signals During the Recovery From General Anesthesia
| NCT ID | NCT06400901 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ruijin Hospital |
| Condition | Deep Brain Stimulation Surgery |
| Study Type | OBSERVATIONAL |
| Enrollment | 42 participants |
| Start Date | 2024-05-15 |
| Primary Completion | 2025-10-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 42 participants in total. It began in 2024-05-15 with a primary completion date of 2025-10-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The correlations of deep brain nuclei firing and cerebral cortex activity during recovery from general anesthesia is unclear. In this study, the local field potential (LFP) from the deep brain nuclei and the scalp electroencephalogram (EEG) of the frontal cortex were recorded from patients undergoing deep brain stimulation (DBS) surgery during the recovery from general anesthesia, in order to explore the changes and relevance of deep brain nuclei firing and cortex activity during the recovery of consciousness from general anesthesia .
Eligibility Criteria
Inclusion Criteria: * 18-75 years old * ASA (American Society of Anesthesiologists) classification I-III * Those who meet the indications for DBS surgery * Right-handed with normal listening and speaking abilities * The patient signs the informed consent form and cooperates with the researchers Exclusion Criteria: * Patients with cognitive impairment \[Montreal Cognitive Assessment (MoCA) score less than 26 points\]; * Patients with severe depression \[Beck Depression Inventory (BDI-II) score greater than or equal to 25 points\]; * Patients with important organs dysfunction, such as heart, lungs, liver, and kidneys; or patients with unstable vital signs; * Patients who are expected to enter the ICU after surgery; * Patients who are alcoholic, alcohol dependent or drug dependent; * Patients who have received general anesthesia one month before surgery, patients who are known to be allergic to general anesthetics; * The DBS surgery exceeds 4 hours; * Patients who are pregnant.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06400901 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Deep Brain Stimulation Surgery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06400901 currently recruiting?
Yes, NCT06400901 is actively recruiting participants. Contact the research team at mx11507@rjh.com.cn for enrollment information.
Where is the NCT06400901 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT06400901 clinical trial?
NCT06400901 is sponsored by Ruijin Hospital. The trial plans to enroll 42 participants.