NCT06896903 Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing
| NCT ID | NCT06896903 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Baylor Research Institute |
| Condition | ANOCA - Angina With Non-obstructive Coronary Arteries |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-05-21 |
| Primary Completion | 2027-05-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2025-05-21 with a primary completion date of 2027-05-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This single-arm, multi-center, prospective study will assess the coronary flow reserve (CFR), index of microcirculatory resistance (IMR), and determinants thereof (transit time, Pa, Pd) in patients before and after intracoronary nitroglycerine.
Eligibility Criteria
Inclusion Criteria: 1. Aged 18 or older 2. Patient being evaluated for ANOCA or INOCA 3. Clinical suspicion for angina 4. Patient should be able to comply with the protocol. 5. Provide written informed consent before study participation. Exclusion Criteria: 1. Existing coronary artery disease 2. Previous percutaneous interventions within the coronaries 3. Current use (within 48 hours) of long-acting nitrate therapies 4. Current use (within 48 hours) of PDE-5 inhibitors (sildenafil, tadalafil) 5. Any other condition or co-morbidity which, in the opinion of the investigator or operator, may pose a significant hazard to the subject if he or she is enrolled in the study. 6. Children below 18 years, prisoners, pregnant people and patients who are unable to provide consent are excluded.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06896903 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying ANOCA - Angina With Non-obstructive Coronary Arteries. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06896903 currently recruiting?
Yes, NCT06896903 is actively recruiting participants. Contact the research team at Bonnie.Ostergren@bswhealth.org for enrollment information.
Where is the NCT06896903 trial being conducted?
This trial is being conducted at Plano, United States.
Who is sponsoring the NCT06896903 clinical trial?
NCT06896903 is sponsored by Baylor Research Institute. The trial plans to enroll 50 participants.