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Recruiting NCT06575439

NCT06575439 An Observational Study of Predictors and Outcomes of Lung Cancer in Never-smokers in the UK

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Clinical Trial Summary
NCT ID NCT06575439
Status Recruiting
Phase
Sponsor University College London Hospitals
Condition Lung Cancer
Study Type OBSERVATIONAL
Enrollment 225 participants
Start Date 2024-09-17
Primary Completion 2029-09

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 225 participants in total. It began in 2024-09-17 with a primary completion date of 2029-09.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this observational study is to improve the early detection of lung cancer in adults who have smoked less than 100 tobacco cigarettes ("never-smokers") in the United Kingdom. The main questions it aims to answer are: * To describe characteristics such as demographics, co-morbidities and environmental exposures * To describe participant pathways including presentation mode and symptoms to understand if earlier diagnosis would be possible * To describe participant outcomes such as cancer stage, treatment and mortality * To quantitatively or qualitatively measure modifiable and non-modifiable factors that may be associated with LCINS including environmental measures, blood tests and genomic data. Participants will currently have no change to their usual care.

Eligibility Criteria

Inclusion Criteria: * All adult participants from age of 18 who are diagnosed or treated with primary lung cancer through radiology or histology at any participating study site Exclusion Criteria: * Participants who have ever smoked cigarettes or tobacco will be excluded; this is defined as: * More than 100 cigarettes or 75g tobacco in their lifetime * Those who have received a prescription for nicotine replacement therapy * For prospective participants, those who cannot consent will be excluded

Contact & Investigator

Central Contact

Neal Navani, PhD

✉ n.navani@ucl.ac.uk

📞 020 7679 2000

Frequently Asked Questions

Who can join the NCT06575439 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06575439 currently recruiting?

Yes, NCT06575439 is actively recruiting participants. Contact the research team at n.navani@ucl.ac.uk for enrollment information.

Where is the NCT06575439 trial being conducted?

This trial is being conducted at London, United Kingdom.

Who is sponsoring the NCT06575439 clinical trial?

NCT06575439 is sponsored by University College London Hospitals. The trial plans to enroll 225 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology