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Recruiting NCT06378632

NCT06378632 AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

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Clinical Trial Summary
NCT ID NCT06378632
Status Recruiting
Phase
Sponsor Cordio Medical
Condition Heart Failure
Study Type OBSERVATIONAL
Enrollment 500 participants
Start Date 2022-02-11
Primary Completion 2025-07-01

Eligibility & Interventions

Sex All sexes
Min Age 22 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Hearo App

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 500 participants in total. It began in 2022-02-11 with a primary completion date of 2025-07-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.

Eligibility Criteria

Major Inclusion Criteria: 1. Age 22 or greater 2. Diagnosed with Symptomatic Chronic Heart Failure \[NYHA II-IVa (ambulatory)\] 3. At least one of the following: 1. One ADHF hospitalization in the last 12 months 2. One unplanned IV/SC diuretic administration in the last 6 months 3. Two unplanned IV/SC diuretic administrations in the last 12 months 4. NTProBNP \>500 pg/ml 4. Clinically stable HF according to investigator discretion 5. Willing to participate as evidenced by signing the written informed consent. Major Exclusion Criteria: 1. Unable to comply with daily use of the App, 2. Has had a major cardiovascular event within 3 months prior to enrolment. 3. Had a Cardiac Resynchronization Therapy Device (CRT) implanted or upgrading ≤ 1 month prior to screening visit. 4. Has estimated Glomerular Filtration Rate (eGFR) \< 30 ml/min/1.73. 5. Is likely to undergo heart transplantation/ LVAD within 6 months of Screening Visit. 6. Was treated for a significant COPD

Contact & Investigator

Central Contact

Bill Tobin

✉ billt@ihcresearch.com

📞 (203) 852-8900

Principal Investigator

Ronit Haviv, PhD

STUDY DIRECTOR

Cordio Medical

Frequently Asked Questions

Who can join the NCT06378632 clinical trial?

This trial is open to participants of all sexes, aged 22 Years or older, studying Heart Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06378632 currently recruiting?

Yes, NCT06378632 is actively recruiting participants. Contact the research team at billt@ihcresearch.com for enrollment information.

Where is the NCT06378632 trial being conducted?

This trial is being conducted at Fairhope, United States, La Jolla, United States, Loma Linda, United States, San Diego, United States and 11 additional locations.

Who is sponsoring the NCT06378632 clinical trial?

NCT06378632 is sponsored by Cordio Medical. The principal investigator is Ronit Haviv, PhD at Cordio Medical. The trial plans to enroll 500 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology