NCT06659835 Amino Acid Loss During Continuous Renal Replacement Therapy
| NCT ID | NCT06659835 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of Vienna |
| Condition | Renal Insufficiency |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-02-08 |
| Primary Completion | 2026-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2025-02-08 with a primary completion date of 2026-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to learn about amino acid loss during continuous renal replacement therapy and plasma amino acid levels in intensive care patients. The main questions it aims to answer are: What amount of amino acids is lost over the duration of continuous renal replacement therapy? How do amino acid plasma concentrations change over time in patients with and without continuous renal replacement therapy? Amino acid concentrations will be measured in the effluent and in the plasma of patients receiving continuous renal replacement therapy as part of their regular medical care. In addition, plasma concentrations of amino acids will be studied in patients without renal replacement therapy.
Eligibility Criteria
Inclusion criteria: * Postoperative ICU patients * Age ≥ 18 years * Patients on enteral or/and parenteral nutrition given according to internal standard operating procedure A) CRRT group: \- CRRT treatment planned; all types of CRRT (continuous veno-venous hemodialysis (CVVHD), continuous veno-venous hemodiafiltration (CVVHDF), continuous veno-venous hemofiltration (CVVH)) B)Non-CRRT group: * no current or previous (\<30 days) continuous or intermittent RRT * no chronic kidney disease stage G3-G5 Exclusion criteria: * Preoperative intensive care patients * Patients with liver cirrhosis stage 1-3 according to the Child-Pugh classification * Patients with acute liver failure
Contact & Investigator
Sarah Yadavalli, Dr.
PRINCIPAL INVESTIGATOR
Medical University of Vienna
Frequently Asked Questions
Who can join the NCT06659835 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Renal Insufficiency. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06659835 currently recruiting?
Yes, NCT06659835 is actively recruiting participants. Contact the research team at sarah.yadavalli@meduniwien.ac.at for enrollment information.
Where is the NCT06659835 trial being conducted?
This trial is being conducted at Vienna, Austria.
Who is sponsoring the NCT06659835 clinical trial?
NCT06659835 is sponsored by Medical University of Vienna. The principal investigator is Sarah Yadavalli, Dr. at Medical University of Vienna. The trial plans to enroll 30 participants.