NCT07193771 Altitude and Outcomes in Pediatric ARDS: A Multicenter Study
| NCT ID | NCT07193771 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Latin American Pediatric Collaborative Network |
| Condition | Respiratory Distress Syndrome, Pediatric |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,600 participants |
| Start Date | 2025-11-01 |
| Primary Completion | 2027-11 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,600 participants in total. It began in 2025-11-01 with a primary completion date of 2027-11.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This multicenter observational study will evaluate the association between geographic altitude, availability of critical care resources, and clinical outcomes in children with pediatric acute respiratory distress syndrome (PARDS). Data on demographics, physiology, and hospital structure will be collected from PICUs located at different altitudes worldwide. The study aims to identify gaps in PARDS management and provide recommendations adapted to diverse resource settings.
Eligibility Criteria
Inclusion Criteria: * Age between 1 month (corrected gestational age) and 18 years. * Admission to a pediatric intensive care unit (PICU) or facility where mechanically ventilated children are cared for. * Requirement of invasive mechanical ventilation. * Diagnosis of pediatric acute respiratory distress syndrome (PARDS) according to PALICC criteria, confirmed within 24 hours before or after endotracheal intubation. Exclusion Criteria: * Patients with active perinatal lung disease (e.g., neonatal respiratory distress syndrome, pulmonary hemorrhage, persistent pulmonary hypertension of the newborn, early bronchopulmonary dysplasia, meconium aspiration). * Patients who have received extracorporeal membrane oxygenation (ECMO) prior to or within the first 24 hours of PARDS diagnosis. * Patients with pre-established limitation of therapeutic effort (LTE) orders or palliative care directives documented before the initiation of invasive mechanical ventilation. * Readmissions to the PICU during the study period (only the first episode per patient will be included).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07193771 clinical trial?
This trial is open to participants of all sexes, aged 1 Month or older, up to 18 Years, studying Respiratory Distress Syndrome, Pediatric. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07193771 currently recruiting?
Yes, NCT07193771 is actively recruiting participants. Contact the research team at pablovasquezmd@gmail.com for enrollment information.
Where is the NCT07193771 trial being conducted?
This trial is being conducted at Sucre, Bolivia, La Paz, Bolivia, Potosí, Bolivia, Tarija, Bolivia and 11 additional locations.
Who is sponsoring the NCT07193771 clinical trial?
NCT07193771 is sponsored by Latin American Pediatric Collaborative Network. The trial plans to enroll 1,600 participants.