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Recruiting NCT04157049

NCT04157049 Alpha-1 Research Registry

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Clinical Trial Summary
NCT ID NCT04157049
Status Recruiting
Phase
Sponsor Alpha-1 Foundation
Condition Alpha 1-Antitrypsin Deficiency
Study Type OBSERVATIONAL
Enrollment 4,000 participants
Start Date 2019-06-20
Primary Completion 2029-06-20

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 4,000 participants in total. It began in 2019-06-20 with a primary completion date of 2029-06-20.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The Alpha-1 Research Registry is a confidential database made up of individuals diagnosed with Alpha-1 Antitrypsin Deficiency (Alpha-1) and individuals identified as Alpha-1 carriers. The Registry was established to facilitate research initiatives and promote the development of improved treatments and a cure for Alpha-1.

Eligibility Criteria

Inclusion Criteria: * Patients diagnosed with Alpha-1 Antitrypsin Deficiency (PiZZ, PiZNull, PiSZ etc.) * Alpha-1 carriers (PiMZ, PiMS etc.) Exclusion Criteria: * Failure to provide informed consent * Normal healthy individuals (MM)

Contact & Investigator

Central Contact

Alison Keaveny, MBBS

✉ akeaveny@alpha1.org

📞 1-877-228-7321

Frequently Asked Questions

Who can join the NCT04157049 clinical trial?

This trial is open to participants of all sexes, studying Alpha 1-Antitrypsin Deficiency. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04157049 currently recruiting?

Yes, NCT04157049 is actively recruiting participants. Contact the research team at akeaveny@alpha1.org for enrollment information.

Where is the NCT04157049 trial being conducted?

This trial is being conducted at Coral Gables, United States.

Who is sponsoring the NCT04157049 clinical trial?

NCT04157049 is sponsored by Alpha-1 Foundation. The trial plans to enroll 4,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology