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Recruiting NCT03845205

NCT03845205 Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH

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Clinical Trial Summary
NCT ID NCT03845205
Status Recruiting
Phase
Sponsor Johns Hopkins University
Condition Alcohol Use Disorder
Study Type INTERVENTIONAL
Enrollment 200 participants
Start Date 2020-11-20
Primary Completion 2027-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Integrated AUD Treatment

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 200 participants in total. It began in 2020-11-20 with a primary completion date of 2027-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Given the severe consequences of alcohol relapse following liver transplantation for alcoholic hepatitis (AH-LT), it is critical to accurately identify alcohol use and implement alcohol interventions early in the post-transplant period to optimize patient outcomes. The proposed randomized clinical trial will examine the implementation and effects of integrated, person- and computer-delivered alcohol treatment compared to standard care on alcohol use (assessed by self-report and biomarker), mood, quality of life and survival following AH-LT. Predictors of 12-month post-transplant alcohol outcomes will be explored to allow future improved tailoring and targeting of these treatments.

Eligibility Criteria

Inclusion Criteria: * English speaking Exclusion Criteria: * too medically/psychiatrically ill to participate * not able to provide informed consent due to cognitive impairment

Contact & Investigator

Central Contact

MARY E MCCAUL, PhD

✉ mmccaul1@jhmi.edu

📞 410-955-9526

Principal Investigator

Mary E McCaul, PhD

PRINCIPAL INVESTIGATOR

Johns Hopkins University

Frequently Asked Questions

Who can join the NCT03845205 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Alcohol Use Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03845205 currently recruiting?

Yes, NCT03845205 is actively recruiting participants. Contact the research team at mmccaul1@jhmi.edu for enrollment information.

Where is the NCT03845205 trial being conducted?

This trial is being conducted at Baltimore, United States.

Who is sponsoring the NCT03845205 clinical trial?

NCT03845205 is sponsored by Johns Hopkins University. The principal investigator is Mary E McCaul, PhD at Johns Hopkins University. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology