NCT06259760 AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia
| NCT ID | NCT06259760 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kaohsiung Medical University Chung-Ho Memorial Hospital |
| Condition | Acute Kidney Injury (Nontraumatic) |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-03-01 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2024-03-01 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This project investigates intentionally hypotensive management such as NTG (nitroglycerin) or NTG+Trandate during general anesthesia in patients undergoing orthognathic surgery. Throughout the entire surgical procedure, blood biochemical and urine monitoring will be conducted. Serum creatinine (Cr) levels, urine analysis, and perioperative monitoring will be utilized as indicators for assessing renal function during the surgery. The objective is to assess its potential renal injury and identify early risk factors for acute kidney injury (AKI). Timely recognition of these factors will allow for the implementation of appropriate intervention strategies, aiding in the prevention of postoperative acute kidney injury. This approach contributes to achieving the goals of Enhanced Recovery After Surgery (ERAS) for surgical patients, promoting faster postoperative recovery.
Eligibility Criteria
Inclusion Criteria: * America society anesthesiologist classification class I to II patients undergoing oro-maxillo-facial surgery * unlimited mouth opening Exclusion Criteria: * patients with arthritis with limited mouth opening * persistent liver dysfunction * chronic renal insufficiency * body mass index ≧35 kg/m2. * past history of malignant hyperthermia or personal or family history * diabetes with insulin treatment * essential hypertension without controlled
Contact & Investigator
Kuang-I Cheng, Phd
PRINCIPAL INVESTIGATOR
Kaohsiung Medical University Chung-Ho Memorial Hospital
Frequently Asked Questions
Who can join the NCT06259760 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Acute Kidney Injury (Nontraumatic). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06259760 currently recruiting?
Yes, NCT06259760 is actively recruiting participants. Contact the research team at kuaich@gmail.com for enrollment information.
Where is the NCT06259760 trial being conducted?
This trial is being conducted at Kaohsiung City, Taiwan.
Who is sponsoring the NCT06259760 clinical trial?
NCT06259760 is sponsored by Kaohsiung Medical University Chung-Ho Memorial Hospital. The principal investigator is Kuang-I Cheng, Phd at Kaohsiung Medical University Chung-Ho Memorial Hospital. The trial plans to enroll 50 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.