NCT07302750 AI-Assisted Relaxation and Breathing Training in Postmenopausal Women
| NCT ID | NCT07302750 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Baskent University |
| Condition | Postmenopausal Period |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2026-04-01 |
| Primary Completion | 2027-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2026-04-01 with a primary completion date of 2027-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate the effectiveness of relaxation and breathing training delivered by a physiotherapist and by an artificial intelligence-assisted system in postmenopausal women with non-specific chronic musculoskeletal pain. Menopause and the postmenopausal period are associated with decreased estrogen levels, structural and functional changes in the musculoskeletal system, increased pain prevalence, reduced muscle function, and impaired quality of life. Relaxation techniques, breathing-focused exercises, and mind-body practices have been shown to reduce pain, improve psychological well-being, and enhance sleep quality. With the growing use of digital health technologies, AI-supported relaxation training may offer personalized guidance, easy accessibility, and sustainable home-based practice, although its effectiveness in postmenopausal women has not yet been demonstrated. In this three-arm randomized controlled trial, participants will be assigned to physiotherapist-led relaxation and breathing training, AI-assisted relaxation and breathing training, or a control group. Interventions will last eight weeks and include sessions three days per week, each approximately 30 minutes. The physiotherapist-guided group will perform sessions face-to-face, while the AI-assisted group will complete prerecorded relaxation and breathing exercises created with AI-generated scripts and voice recordings. The control group will continue daily routines without structured training during the study period. Assessments will be conducted at baseline and at the end of eight weeks. Outcome measures will include pain severity, pressure pain threshold, musculoskeletal symptoms, menopause-specific quality of life, psychological status, sleep quality, dyspnea, and participant satisfaction. The study aims to compare the effects of physiotherapist-led and AI-assisted training modalities on pain, musculoskeletal health, sleep, psychological well-being, and quality of life. Findings are expected to contribute to the development of accessible and cost-effective interventions that support symptom management and improve the daily functioning of postmenopausal women.
Eligibility Criteria
Inclusion Criteria: * Women aged 45 to 65 years * Being in natural menopause (no menstrual bleeding for at least 12 months) * Having non-specific chronic musculoskeletal pain for at least 3 months (reporting a pain intensity of at least 4 cm on the VAS) * Using only standard analgesic medications for pain management * Being literate * Owning a smartphone or tablet, having the ability to listen to audio recordings, and having adequate skills to participate in online sessions * Being willing to participate in the study and providing written informed consent Exclusion Criteria: * Surgical or medication-induced menopause * Regular use of opioid analgesics, anticonvulsants, antidepressants, or similar medications * Uncontrolled advanced cardiovascular, oncological, metabolic, rheumatologic, or neurological diseases * Body Mass Index (BMI) of 40 kg/m² or higher * History of major surgery or severe trauma within the past 3 months
Contact & Investigator
Neslihan Durutürk, Prof. Dr.
STUDY DIRECTOR
Başkent University, Faculty of Health Sciences, Department of Physical Therapy and Rehabilitation
Frequently Asked Questions
Who can join the NCT07302750 clinical trial?
This trial is open to female participants only, aged 45 Years or older, up to 65 Years, studying Postmenopausal Period. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07302750 currently recruiting?
Yes, NCT07302750 is actively recruiting participants. Contact the research team at nalkan@baskent.edu.tr for enrollment information.
Where is the NCT07302750 trial being conducted?
This trial is being conducted at Ankara, Turkey (Türkiye).
Who is sponsoring the NCT07302750 clinical trial?
NCT07302750 is sponsored by Baskent University. The principal investigator is Neslihan Durutürk, Prof. Dr. at Başkent University, Faculty of Health Sciences, Department of Physical Therapy and Rehabilitation. The trial plans to enroll 48 participants.