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Recruiting NCT07122427

NCT07122427 Aging of the Vascular Wall

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Clinical Trial Summary
NCT ID NCT07122427
Status Recruiting
Phase —
Sponsor Centre Hospitalier Universitaire de Saint Etienne
Condition Vascular Risk
Study Type OBSERVATIONAL
Enrollment 30 participants
Start Date 2025-07-17
Primary Completion 2026-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Graft collection

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 30 participants in total. It began in 2025-07-17 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Demographic aging is predicted to be one of the most significant social changes of the 21st century. Aging is a slow, multifactorial process that progressively impacts the integrity of cells, tissues, and organs. This decline in function increases the risk of numerous diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases (CVD). CVD, the leading global cause of death, becomes more prevalent with age. Aging contributes to endothelial dysfunction, vessel stiffness, thickening, and impaired platelet function. These changes disrupt hemostatic processes and increase the risk of cardiovascular complications. Despite preventive strategies CVD remain a major public health challenge. Cellular aging, or senescence, affects all cell types, particularly endothelial cells and platelets. However, little research has compared the aging rates of different blood vessel types, such as arteries and veins. Given their distinct compositions and developmental origins, it is likely that their aging processes differ at molecular, cellular, and physiological levels.

Eligibility Criteria

Inclusion Criteria: * Major patients requiring coronary artery bypass grafting (CABG). Exclusion Criteria: * Hypertension, diabetes, systemic inflammatory disease.

Contact & Investigator

Central Contact

Anne-Claire DUCHEZ, PhD

✉ anne-claire.duchez@efs.sante.fr

📞 (0)477421423

Principal Investigator

Salvatore CAMPISI, MD

PRINCIPAL INVESTIGATOR

Centre Hospitalier Universitaire de Saint Etienne

Frequently Asked Questions

Who can join the NCT07122427 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Vascular Risk. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07122427 currently recruiting?

Yes, NCT07122427 is actively recruiting participants. Contact the research team at anne-claire.duchez@efs.sante.fr for enrollment information.

Where is the NCT07122427 trial being conducted?

This trial is being conducted at Saint-Etienne, France.

Who is sponsoring the NCT07122427 clinical trial?

NCT07122427 is sponsored by Centre Hospitalier Universitaire de Saint Etienne. The principal investigator is Salvatore CAMPISI, MD at Centre Hospitalier Universitaire de Saint Etienne. The trial plans to enroll 30 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology