NCT06643403 Age-related Changes in Retinal Oxygen Extraction in Healthy Subjects
| NCT ID | NCT06643403 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of Vienna |
| Condition | Healthy Participants |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-09-30 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2024-09-30 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
It has been found that several systemic and ocular diseases are associated with impaired retinal oxygen extraction. In the present study, retinal oxygen extraction will be measured in different age groups in order to identify age related changes in otherwise healthy subjects. In addition, the study will explore short-term changes in retinal metabolism induced by breathing pure oxygen. Measurements will be performed with dynamic vessel analyzer and laser speckle flowgraphy to evaluate retinal blood flow and retinal oxygen saturation, in order to calculate retinal oxygen extraction.
Eligibility Criteria
Inclusion Criteria: * Men and women aged between 18 and 80 years * Signed informed consent * Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant for the purpose of the study * Normal findings in the medical history, unless the investigator considers an abnormality to be clinically irrelevant for the purpose of the study * Nonsmokers Exclusion Criteria: * Abuse of alcoholic beverages or drugs * Participation in a clinical trial in the 3 weeks preceding the study * Symptoms of a clinically relevant illness in the 3 weeks before the first study day * Blood donation during the previous 3 weeks * Pregnant or breast-feeding women
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06643403 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Healthy Participants. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06643403 currently recruiting?
Yes, NCT06643403 is actively recruiting participants. Contact the research team at doreen.schmidl@meduniwien.ac.at for enrollment information.
Where is the NCT06643403 trial being conducted?
This trial is being conducted at Vienna, Austria.
Who is sponsoring the NCT06643403 clinical trial?
NCT06643403 is sponsored by Medical University of Vienna. The trial plans to enroll 50 participants.