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Recruiting NCT04649125

Advanced Techniques For Single-fraction Palliative Radiotherapy Versus Standard Multi Fraction Radiation

Trial Parameters

Condition Palliative Radiotherapy
Sponsor Royal North Shore Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age N/A
Max Age N/A
Start Date 2021-05-31
Completion 2026-06-30
Interventions
dose escalation

Brief Summary

The aim of the study is to determine if single fraction dose escalated palliative radiotherapy results in a prolonged duration of benefit for patients otherwise suitable for Multifraction (5-10#) palliative radiation. The primary endpointis to determine the percentage of patients who have achieved a substantial benefit from palliative radiotherapy and have not redeveloped symptoms by 12 months post treatment

Eligibility Criteria

Inclusion Criteria: * Metastatic cancer * Recommended for 5-10 fractions palliative radiation * Patients with spinal cord compression are eligible for enrolment Exclusion Criteria: * Unwilling or unable to give informed consent * Patients who are recommended for single fraction palliative radiation

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