NCT07471386 Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis
| NCT ID | NCT07471386 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Gazi University |
| Condition | Peri-implantitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-03-01 |
| Primary Completion | 2027-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-03-01 with a primary completion date of 2027-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to increase the width and thickness of peri-implant keratinized mucosa (KM) by transferring a properly dimensioned free gingival graft (FGG) from the palatal donor site and to evaluate its effect as an adjunctive approach to non-surgical peri-implantitis therapy. The procedure is indicated for patients diagnosed with peri-implantitis who present with an inadequate KM (midbuccal KM height \< 2 mm). One month after non-surgical therapy, patients in the test group will undergo keratinized mucosa augmentation using an FGG, while patients in the control group will continue with supportive periodontal therapy and regular follow-up visits. The primary outcome measure of the study is the change in probing depth (PD) at 12 months following peri-implantitis treatment.
Eligibility Criteria
Inclusion Criteria: * Non-smoker * Systemically healthy * Keratinized mucosa witdh \< 2 mm Exclusion Criteria: * İntake of medications that impede periodontal tissue health and healing * Pregnancy or lactation
Contact & Investigator
Sila Cagri Isler, Prof Dr
STUDY DIRECTOR
Gazi University Faculty of Dentistry
Frequently Asked Questions
Who can join the NCT07471386 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Peri-implantitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07471386 currently recruiting?
Yes, NCT07471386 is actively recruiting participants. Contact the research team at silaisler@gazi.edu.tr for enrollment information.
Where is the NCT07471386 trial being conducted?
This trial is being conducted at Ankara, Turkey (Türkiye).
Who is sponsoring the NCT07471386 clinical trial?
NCT07471386 is sponsored by Gazi University. The principal investigator is Sila Cagri Isler, Prof Dr at Gazi University Faculty of Dentistry. The trial plans to enroll 30 participants.