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Recruiting NCT06973759

NCT06973759 Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness

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Clinical Trial Summary
NCT ID NCT06973759
Status Recruiting
Phase
Sponsor Chinese University of Hong Kong
Condition Depression, Unipolar
Study Type INTERVENTIONAL
Enrollment 90 participants
Start Date 2025-11-01
Primary Completion 2028-06-30

Trial Parameters

Condition Depression, Unipolar
Sponsor Chinese University of Hong Kong
Study Type INTERVENTIONAL
Phase N/A
Enrollment 90
Sex ALL
Min Age 12 Years
Max Age 19 Years
Start Date 2025-11-01
Completion 2028-06-30
Interventions
Bright light therapyDim red light

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Brief Summary

This study examines the efficacy of bright light therapy as a treatment for adolescents diagnosed with unipolar non-seasonal depression who exhibit an evening chronotype.

Eligibility Criteria

Inclusion Criteria: 1. Chinese, aged 12-19 years old; 2. Written informed assent/consent of participation into the study is given by the participant and his/her parent or guardian (for those aged under 18), respectively; 3. Having a DSM-5 diagnosis of unipolar non-seasonal depression as confirmed by the Chinese version of the Kiddie-Schedule for Affective Disorders and Schizophrenia (K-SADS) psychiatric interview, DSM-5 Seasonal specifier, AND having a score on Children's Depression Rating Scale (CDRS-R) at least 40; 4. Being classified as evening chronotype according to the score on the reduced Horne-Östberg Morning-Eveningness Questionnaire (rMEQ), i.e. \<12. Exclusion Criteria: 1. A current diagnosis of substance abuse or dependence; a current or past history of manic or hypomanic episode, schizophrenia spectrum disorders, organic mental disorders, or intellectual disabilities; 2. Having a clinically significant suicidality (presence of suicidal ideation with a plan or an attempt) a

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