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Recruiting NCT06538415

Adding Polyphenol-rich Pulses to Daily Diet Improves Skin Health by Reshaping the Skin Microbiome

Trial Parameters

Condition Healthy
Sponsor University of Florida
Study Type INTERVENTIONAL
Phase N/A
Enrollment 50
Sex FEMALE
Min Age 45 Years
Max Age 65 Years
Start Date 2026-03-01
Completion 2026-12-31
Interventions
Pulse DietControl Rice Diet

Brief Summary

Skin health is influenced by the microbiome, lipids, oxidative stress, inflammation, and UV exposure. A 14-week trial with 50 women aged 45-65 will test if polyphenol-rich pulses improve skin health by affecting these factors. Using a white rice control diet, the study will measure skin parameters and analyze correlations with changes in lipids and microbiome, potentially proving the benefits of pulses.

Eligibility Criteria

Inclusion Criteria: * BMI (18.5-29.9) * Body weight ≥110 pounds * Fitzpatrick skin type 2 and 3. Exclusion Criteria: * pregnancy * breast-feeding * impaired fasting glucose * frequent alcohol use * history of skin cancer * sunbathing and the use of tanning bed, intake of vitamin/mineral supplements * habitual high intake of fruits (≥ 2 cups daily) * intake of medication that might influence the outcome of the study

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