NCT05838235 Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome
| NCT ID | NCT05838235 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Toulouse |
| Condition | Marfan Syndrome |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2023-04-24 |
| Primary Completion | 2028-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2023-04-24 with a primary completion date of 2028-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This research study aims to evaluate the effect of a 6-month adapted physical activity program (APA) on the endurance capacities (evaluated as the maximum oxygen consumption \[VO2 peak\] on a cardiopulmonary exercise test) of children and adolescents with Marfan syndrome or related.
Eligibility Criteria
Inclusion Criteria: * Genetically confirmed Marfan syndrome or related syndrome * Girl or boy aged 7 to 17 * Informed and written consent signed by at least one of the two holders of parental authority * Patient affiliated to a social security scheme or equivalent Exclusion Criteria: * Cardiac contraindications to the APA program: * Severe aortic dilation (aortic diameter \> 45 mm) * and/or left ventricular failure (left ventricular ejection fraction \<45%) * and/or severe mitral leakage ≥ grade 3 * Pregnancy
Contact & Investigator
Thomas EDOUARD, MD
PRINCIPAL INVESTIGATOR
University Hospital, Toulouse
Frequently Asked Questions
Who can join the NCT05838235 clinical trial?
This trial is open to participants of all sexes, aged 7 Years or older, up to 17 Years, studying Marfan Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05838235 currently recruiting?
Yes, NCT05838235 is actively recruiting participants. Contact the research team at edouard.t@chu-toulouse.fr for enrollment information.
Where is the NCT05838235 trial being conducted?
This trial is being conducted at Toulouse, France.
Who is sponsoring the NCT05838235 clinical trial?
NCT05838235 is sponsored by University Hospital, Toulouse. The principal investigator is Thomas EDOUARD, MD at University Hospital, Toulouse. The trial plans to enroll 30 participants.