NCT07580040 Acute Ocular Effects of Cigarette Smoking
| NCT ID | NCT07580040 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Istanbul University |
| Condition | Smoking ( Cigarette) |
| Study Type | OBSERVATIONAL |
| Enrollment | 90 participants |
| Start Date | 2026-02-15 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 90 participants in total. It began in 2026-02-15 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective study aims to evaluate the short-term effects of smoking on corneal tomographic and biometric measurements in healthy adults. After baseline examinations and measurements are taken in both smoking and non-smoking participants, the same measurements will be repeated after 10 minutes of external exposure, and within-group and between-group changes will be compared. The aim of the study is to determine whether acute smoking exposure leads to measurable immediate changes in corneal tomographic and biometric parameters.
Eligibility Criteria
Inclusion Criteria: * Healthy adults aged 18 to 60 years * Current smokers in the smoking group * Never-smokers in the control group * Willing and able to undergo ophthalmic examination and Pentacam AXL measurements Exclusion Criteria: * History of ocular surgery or ocular trauma * Presence of corneal disease, retinal disease, or ocular surface disorder * Clinically significant dry eye disease * Contact lens use within the last 2 weeks * Use of medications that may affect the ocular surface or pupillary dynamics, including anticholinergics or sympathomimetics * Systemic diseases such as diabetes mellitus or hypertension * Former smoking history in the control group * Use of electronic cigarettes or other tobacco products * Inability to cooperate adequately for accurate measurement
Contact & Investigator
Semih Çakmak
PRINCIPAL INVESTIGATOR
Istanbul University
Frequently Asked Questions
Who can join the NCT07580040 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Smoking ( Cigarette). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07580040 currently recruiting?
Yes, NCT07580040 is actively recruiting participants. Contact the research team at semihcakmak@istanbul.edu.tr for enrollment information.
Where is the NCT07580040 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07580040 clinical trial?
NCT07580040 is sponsored by Istanbul University. The principal investigator is Semih Çakmak at Istanbul University. The trial plans to enroll 90 participants.