NCT07718048 Acute Effects of MCT Formulations on Beta-Hydroxybutyrate Response, Lipid Profile, and Glucose Levels in Healthy Adults
| NCT ID | NCT07718048 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Milan |
| Condition | Ketone Body |
| Study Type | INTERVENTIONAL |
| Enrollment | 12 participants |
| Start Date | 2026-01-13 |
| Primary Completion | 2026-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 12 participants in total. It began in 2026-01-13 with a primary completion date of 2026-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to evaluate the effects of medium-chain triglycerides (MCTs), delivered in different formulations, on beta-hydroxybutyrate response (as a marker of ketone body production), lipid metabolism, and glucose responses in healthy adults. The main questions it aims to answer are: Do MCTs influence beta-hydroxybutyrate responses, lipid metabolism, and glucose responses differently compared to long-chain triglycerides (LCTs)? Do different types of MCTs (natural sources containing C8 to C12 versus synthetic formulations containing only C8 and C10) lead to different beta-hydroxybutyrate, lipid, and glucose responses? Does the form in which MCTs are consumed (e.g., powders or incorporated into foods) influence beta-hydroxybutyrate production, lipid metabolism, and glucose responses? Researchers will compare five different lipid formulations to evaluate their effects on postprandial beta-hydroxybutyrate concentrations, blood lipid levels, and glucose. Participants will: Consume five different test products on separate study visits. Provide blood samples for up to five hours after each intake for metabolic measurements.
Eligibility Criteria
Inclusion Criteria: * Healthy adult participants * Age between 18 and 40 years * Ability to understand the study procedures and provide informed consent Exclusion Criteria: * Alterations in glucose or lipid metabolism * Diseases requiring the use of medications that affect glucose or lipid metabolism * Reported or diagnosed malabsorption conditions * Pregnancy or breastfeeding
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07718048 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Ketone Body. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07718048 currently recruiting?
Yes, NCT07718048 is actively recruiting participants. Contact the research team at alessandro.leone1@unimi.it for enrollment information.
Where is the NCT07718048 trial being conducted?
This trial is being conducted at Milan, Italy.
Who is sponsoring the NCT07718048 clinical trial?
NCT07718048 is sponsored by University of Milan. The trial plans to enroll 12 participants.