NCT06868862 Acute Effects of Isoenergetic HIIE Vs. MICE on Key Parameters of Fat Mass Loss in Young Females with Overweight or Obesity
| NCT ID | NCT06868862 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques |
| Condition | Overweight and Obese Adults |
| Study Type | INTERVENTIONAL |
| Enrollment | 15 participants |
| Start Date | 2025-02-01 |
| Primary Completion | 2025-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 15 participants in total. It began in 2025-02-01 with a primary completion date of 2025-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases. Managing obesity effectively requires lifestyle and dietary modifications, including increased physical activity. Among the various exercise strategies, Moderate-Intensity Continuous Training (MICT) and High-Intensity Interval Training (HIIT) are widely recommended for reducing FM. Compared to MICT, HIIT is a time-efficient approach, often perceived as more enjoyable, and has been shown to promote greater total and abdominal fat loss in a shorter period. However, the precise mechanisms underlying this enhanced fat loss remain unclear. This study aims to compare the acute effects of two isoenergetic exercise sessions - MICE (Moderate-Intensity Continuous Exercise) and HIIE (High-Intensity Interval Exercise) - on key physiological responses involved in fat mass loss. Specifically, we will assess plasma catecholamine levels during exercise and recovery, as well as oxygen consumption, substrate oxidation, and appetite over the 2-hour post-exercise period in young females with overweight or obesity. By elucidating the role of catecholaminergic stimulation as a potential regulator of fat mass loss, this research could provide valuable insights for optimizing exercise strategies in weight management and metabolic health.
Eligibility Criteria
Inclusion Criteria: * women with overwieght or obesity (BMI: 25-35 kg/m²) Exclusion Criteria: * contraceptive use * menopause * irregular menstrual cycle * medical contraindications to intense physical activity, * painful joints, * taking ß-blocker
Frequently Asked Questions
Who can join the NCT06868862 clinical trial?
This trial is open to female participants only, aged 20 Years or older, up to 45 Years, studying Overweight and Obese Adults. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06868862 currently recruiting?
Yes, NCT06868862 is actively recruiting participants. Visit ClinicalTrials.gov or contact Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques to inquire about joining.
Where is the NCT06868862 trial being conducted?
This trial is being conducted at São Paulo, Brazil.
Who is sponsoring the NCT06868862 clinical trial?
NCT06868862 is sponsored by Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques. The trial plans to enroll 15 participants.