NCT07683351 Active Oxygen Gel Versus Hyaluronic Acid Gel for Palatal Wound Healing After Free Gingival Graft
| NCT ID | NCT07683351 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Suez Canal University |
| Condition | Palatal Wound Healing |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-08-27 |
| Primary Completion | 2026-08-27 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-08-27 with a primary completion date of 2026-08-27.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled clinical trial aims to evaluate and compare the effectiveness of different palatal dressing materials on wound healing following free gingival graft harvesting. Thirty systemically healthy patients with mucogingival defects requiring free gingival graft procedures will be enrolled from the outpatient clinic of the Department of Oral Medicine and Periodontology, Faculty of Dentistry, Suez Canal University. Patients will be randomly allocated into three equal groups (10 patients each). Group A (control) will receive a gelatin sponge with flowable composite on the donor site. Group B will receive hyaluronic acid gel covered with a gelatin sponge and flowable composite. Group C will receive active oxygen gel covered with a gelatin sponge and flowable composite. Postoperative outcomes will be assessed in terms of pain (visual analog scale), analgesic consumption, clinical wound healing (Landry healing index), complete wound re-epithelialization (hydrogen peroxide test), dimensional changes of the wound, and occurrence of complications. Evaluations will be performed at baseline and during follow-up visits up to four weeks postoperatively. The study aims to determine which dressing material provides better postoperative comfort and enhances palatal wound healing after free gingival graft procedures.
Eligibility Criteria
Inclusion Criteria: Systemically healthy patients Age between 18 and 60 years Patients with mucogingival defects requiring free gingival graft Adequate palatal thickness (\>3 mm) Cooperative and motivated patients Good oral hygiene compliance Exclusion Criteria: Systemic diseases that contraindicate surgical procedures Smokers Pregnant or lactating females Immunocompromised patients Patients undergoing chemotherapy or radiotherapy Poor oral hygiene or non-compliant patients Palatal infection
Frequently Asked Questions
Who can join the NCT07683351 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Palatal Wound Healing. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07683351 currently recruiting?
Yes, NCT07683351 is actively recruiting participants. Visit ClinicalTrials.gov or contact Suez Canal University to inquire about joining.
Where is the NCT07683351 trial being conducted?
This trial is being conducted at Ismailia, Egypt.
Who is sponsoring the NCT07683351 clinical trial?
NCT07683351 is sponsored by Suez Canal University. The trial plans to enroll 30 participants.