NCT06667674 A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT
| NCT ID | NCT06667674 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Uppsala University |
| Condition | Prolonged Grief Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 270 participants |
| Start Date | 2025-04-23 |
| Primary Completion | 2027-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 270 participants in total. It began in 2025-04-23 with a primary completion date of 2027-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to evaluate the effectiveness of internet-delivered Cognitive Behavioral Therapy (iCBT) in reducing symptoms of prolonged grief in adults diagnosed with prolonged grief disorder. The main questions the study aims to answer are: * Does iCBT reduce symptoms of prolonged grief disorder, posttraumatic stress, and depression following the death of a loved one in the short and long term? * What mechanisms contribute to the effectiveness of iCBT in treating prolonged grief disorder? The iCBT intervention will be compared to a waitlist control group and an active control group to see if iCBT reduces symptoms of prolonged grief disorder more effectively than no treatment or a placebo treatment. Participants will: * Be randomly assigned to either the iCBT group, an active control group or a waitlist control group * Complete online assessments of symptom severity, grief cognitions, and level of avoidance before, during and after intervention * Engage in 10 weeks of a therapist-guided online treatment
Eligibility Criteria
Inclusion Criteria: * Currently residing in Sweden * Lost a relative or close friend to any cause of death at least six months ago * Suffers from prolonged grief disorder Exclusion Criteria: * Ongoing severe psychiatric problems that may prevent treatment implementation or require more urgent care (e.g., participants with untreated psychotic disorder, untreated bipolar disorder, ongoing substance abuse, elevated suicide risk) * Change in dosage of any medication for mental health issues (e.g., antidepressant medication) in the past four weeks or in the next two months
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06667674 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Prolonged Grief Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06667674 currently recruiting?
Yes, NCT06667674 is actively recruiting participants. Contact the research team at josefin.sveen@uu.se for enrollment information.
Where is the NCT06667674 trial being conducted?
This trial is being conducted at Uppsala, Sweden, Uppsala, Sweden.
Who is sponsoring the NCT06667674 clinical trial?
NCT06667674 is sponsored by Uppsala University. The trial plans to enroll 270 participants.