NCT07312123 A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome
| NCT ID | NCT07312123 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hospital Universiti Sains Malaysia |
| Condition | Carpal Tunnel Syndrome |
| Study Type | INTERVENTIONAL |
| Enrollment | 84 participants |
| Start Date | 2025-12-08 |
| Primary Completion | 2026-12-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 84 participants in total. It began in 2025-12-08 with a primary completion date of 2026-12-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Carpal Tunnel Syndrome (CTS) is a common condition that causes numbness, tingling, pain, and weakness in the hand due to compression of the median nerve at the wrist. It can affect daily activities, work performance, and quality of life. While surgery is effective in severe cases, many patients with mild to moderate CTS are initially treated with non-surgical options such as splinting and medications. However, the effectiveness of oral supplements for CTS remains uncertain. This clinical study aims to evaluate whether an oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B complex can safely reduce symptoms and improve hand function in patients with Carpal Tunnel Syndrome. These supplements are believed to have antioxidant, anti-inflammatory, and nerve-protective properties, which may help reduce nerve irritation and improve nerve recovery. Participants in this study will be randomly assigned to receive either the oral supplement combination or a comparator treatment. The study is single-blinded, meaning participants will not know which treatment they are receiving. Symptoms such as pain, numbness, and hand function will be assessed over a defined follow-up period using clinical evaluation and standardized questionnaires. The main hypothesis of this study is that patients receiving the oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B will experience greater improvement in symptoms and functional outcomes compared to those who do not receive the combination, without significant side effects. The results of this study may help determine whether this oral supplement combination can be used as an effective and safe conservative treatment option for patients with Carpal Tunnel Syndrome, potentially reducing the need for invasive procedures.
Eligibility Criteria
Inclusion Criteria: * Age more than 18 years old * Subjects with symptoms and physical examination of CTS * Patients with CTS going for CT release Exclusion Criteria: * Pregnant or breast-feeding women * Patients with history of trauma in the dominant hand
Contact & Investigator
nurhakim bin ibrahim
PRINCIPAL INVESTIGATOR
Hospital Pakar Universiti Sains Malaysia
Frequently Asked Questions
Who can join the NCT07312123 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Carpal Tunnel Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07312123 currently recruiting?
Yes, NCT07312123 is actively recruiting participants. Contact the research team at nurhakimibrahim@gmail.com for enrollment information.
Where is the NCT07312123 trial being conducted?
This trial is being conducted at Kubang Kerian, Malaysia.
Who is sponsoring the NCT07312123 clinical trial?
NCT07312123 is sponsored by Hospital Universiti Sains Malaysia. The principal investigator is nurhakim bin ibrahim at Hospital Pakar Universiti Sains Malaysia. The trial plans to enroll 84 participants.