A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants
Trial Parameters
Brief Summary
The primary purpose of the study is to characterise the safety of GSK4024484 in healthy participants within a controlled pharmacokinetic (PK) range.
Eligibility Criteria
Inclusion Criteria: 1. Participant must be 18 to 60 years of age inclusive, at the time of signing the informed consent. 2. Participants who are considered healthy as determined by medical evaluation including medical history, physical examination, laboratory tests, and cardiac assessment. 3. A participant with a clinical abnormality or laboratory parameter(s) which is/are not specifically listed in the inclusion or exclusion criteria, or outside the normal reference range for the population being studied, may be included only if the Investigator considers, that the finding is unlikely to introduce additional risk factors for the participant and will not interfere with the study procedures or endpoints. 4. ALT (Alanine transaminase) and AST (Aspartate transaminase) within the normal range at screening. 5. Total bilirubin within the normal range unless the participant is known to have Gilbert's syndrome. 6. Body weight ≥50kg, and BMI within the range 19 to 32 kilogram per square metre (