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Recruiting Phase 1 NCT07447856

A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain

Trial Parameters

Condition Cancer Patients
Sponsor Memorial Sloan Kettering Cancer Center
Study Type INTERVENTIONAL
Phase Phase 1
Enrollment 150
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2026-02-23
Completion 2028-02
Interventions
Topical herbal plaster

Brief Summary

The are doing this study to find out whether using topical (on the skin) herbal plasters, Tibetree pain- relieving plasters (PRPs), can be an effective addition to standard opioid therapy for pain management. The researchers will look at whether the Tibetree PRPs are a practical (feasible) and effective way of managing localized pain (pain that is limited to a certain area) in people who are currently taking opioids. Participants in this study will have cancer or have had it in the past.

Eligibility Criteria

Inclusion Criteria: * English speaking with age ≥ 18 years or older * A diagnosis of cancer with no restrictions placed on type of cancer or stage. Eligibility criteria will not be restricted to MSK confirmed biopsy/diagnosis. Outside institution's testing is sufficient. * Ambulatory (Karnofsky Performance Status of ≥ 60) * Having one of three types of pain (e.g., musculoskeletal pain, bone metastasis pain, and visceral/abdominal pain) and the worst pain area can be covered by one patch of topical herbal plaster * Worst pain score (measured by the 0-10 numeric pain rating scale) 4 or above in the preceding week * Current use of short-term oral opioids (i.e. oxycodone, morphine immediate release, or hydromorphone) for pain management. * Willingness to adhere to and understanding of all study-related procedures, including randomization to one of the two possible study arms * Able to understand informed consent and provide signed informed consent form Exclusion Criteria: * Patients are un

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