NCT06193499 A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
| NCT ID | NCT06193499 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Karolinska Institutet |
| Condition | Osteoarthritis Thumb |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2024-01-17 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2024-01-17 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
Eligibility Criteria
Inclusion Criteria: * Osteoarthritis in the thumb base * Radiological Eaton Littler class 1-3. * Clinical signs of thumb base osteoarthritis )pain at palpation of the CMC-1 joint and pain during provocation/grinding test). Exclusion Criteria: * Rheumatoid arthritis * Ongoing infection in the hand or wrist * History of gout or pseudogout in the hand * Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction). * Chronic pain syndrome / centralized pain. * Intra-articular injection in the affected joint within 6 months. * Eaton Littler class 4 (symptomatic STT joint osteoarthritis).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06193499 clinical trial?
This trial is open to participants of all sexes, studying Osteoarthritis Thumb. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06193499 currently recruiting?
Yes, NCT06193499 is actively recruiting participants. Contact the research team at maria.wilcke@regionstockholm.se for enrollment information.
Where is the NCT06193499 trial being conducted?
This trial is being conducted at Stockholm, Sweden.
Who is sponsoring the NCT06193499 clinical trial?
NCT06193499 is sponsored by Karolinska Institutet. The trial plans to enroll 90 participants.