A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
Trial Parameters
Brief Summary
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
Eligibility Criteria
Inclusion Criteria: * Osteoarthritis in the thumb base * Radiological Eaton Littler class 1-3. * Clinical signs of thumb base osteoarthritis )pain at palpation of the CMC-1 joint and pain during provocation/grinding test). Exclusion Criteria: * Rheumatoid arthritis * Ongoing infection in the hand or wrist * History of gout or pseudogout in the hand * Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction). * Chronic pain syndrome / centralized pain. * Intra-articular injection in the affected joint within 6 months. * Eaton Littler class 4 (symptomatic STT joint osteoarthritis).