NCT07363824 A Study on the Correlation Between Tear Iron Levels and the Severity of Dry Eye Disease.
| NCT ID | NCT07363824 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shanghai Changzheng Hospital |
| Condition | Dry Eye Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 52 participants |
| Start Date | 2026-02-06 |
| Primary Completion | 2029-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 52 participants in total. It began in 2026-02-06 with a primary completion date of 2029-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to see if the amount of iron in tears is linked to how severe dry eye disease is. We hope this can lead to a new way to help diagnose and understand dry eye. This is an observational study. We will compare tear samples from people with dry eye to samples from people with healthy eyes. We will measure the iron content in the tears and see if it correlates with standard dry eye test results and symptom scores.
Eligibility Criteria
Inclusion Criteria: * Aged between 18 and 70 years, inclusive. * Willing and able to provide written informed consent. Exclusion Criteria: * History or clinical suspicion of significant systemic conditions: hematologic diseases, severe systemic infections, malignancies (treated or untreated), or chronic hepatic/renal insufficiency. * Use of artificial tears or any topical eye drops within 2 hours prior to examination. * Active ocular allergy, infection, or severe blepharitis within the past 1 month. * Systemic or topical use of antibiotics, corticosteroids, NSAIDs, or immunosuppressants within the past 1 month. * History of contact lens wear within the past 1 month. * History of blood transfusion, ocular surgery, or significant ocular trauma within the past 6 months. * Women who are pregnant, breastfeeding, or postmenopausal women undergoing hormone replacement therapy. * Known hypersensitivity to fluorescein sodium.
Frequently Asked Questions
Who can join the NCT07363824 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Dry Eye Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07363824 currently recruiting?
Yes, NCT07363824 is actively recruiting participants. Visit ClinicalTrials.gov or contact Shanghai Changzheng Hospital to inquire about joining.
Where is the NCT07363824 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT07363824 clinical trial?
NCT07363824 is sponsored by Shanghai Changzheng Hospital. The trial plans to enroll 52 participants.