NCT06447714 A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.
| NCT ID | NCT06447714 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Zhujiang Hospital |
| Condition | Cotinine Levels |
| Study Type | OBSERVATIONAL |
| Enrollment | 450 participants |
| Start Date | 2022-09-01 |
| Primary Completion | 2027-03-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 450 participants in total. It began in 2022-09-01 with a primary completion date of 2027-03-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing. The enrolled patients underwent high-resolution magnetic resonance angiography to detect whether the intracranial aneurysm wall was enhanced and classify the degree of enhancement. The purpose is to study the correlation between arterial aneurysm wall enhancement and cotinine levels
Eligibility Criteria
Inclusion Criteria: * Age 18-75 years old, male or infertile female; * Diagnosed as IA (intracranial aneurysm) through CTA, MRA, or DSA; And it is suitable for endovascular intervention treatment * The patient and/or their legal representative or guardian fully understand the research purpose, voluntarily participate and sign informed consent Books; * Patients willing to cooperate with high-resolution magnetic resonance imaging. * Patients willing to follow up and evaluate according to clinical research protocol requirements Exclusion Criteria: * AVM (arteriovenous malformation), Moyamoya disease, or DAVF (dural arteriovenous fistula) related aneurysms; * Patients with contraindications for high-resolution magnetic resonance imaging; * Participants in clinical trials of other drugs or medical devices; * Patients with severe underlying diseases and extremely poor clinical conditions who cannot tolerate general anesthesia surgery; * Patients with poor compliance and inability to cooperate with follow-up; * Possible or clear history of severe allergy to contrast agents; * Patients with a life expectancy of less than 2 years; * Women who are breastfeeding and preparing for pregnancy during the study period
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06447714 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Cotinine Levels. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06447714 currently recruiting?
Yes, NCT06447714 is actively recruiting participants. Contact the research team at 13681134001@163.com for enrollment information.
Where is the NCT06447714 trial being conducted?
This trial is being conducted at Guangzhou, China.
Who is sponsoring the NCT06447714 clinical trial?
NCT06447714 is sponsored by Zhujiang Hospital. The trial plans to enroll 450 participants.