NCT07309250 A Study on Gastrointestinal Transit Time at the Population Level
| NCT ID | NCT07309250 |
| Status | Recruiting |
| Phase | — |
| Sponsor | KU Leuven |
| Condition | Gastrointestinal Transit Time |
| Study Type | OBSERVATIONAL |
| Enrollment | 932 participants |
| Start Date | 2025-12-01 |
| Primary Completion | 2026-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 932 participants in total. It began in 2025-12-01 with a primary completion date of 2026-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this study is to investigate the baseline of gastrointestinal transit time (GITT) and explore its relationship with other health indicators in 932 healthy adult volunteers. The main questions it aims to answer are: What are the population-level baseline values for GITT using the blue dye method? How is GITT associated with key physiological parameters including blood metabolic markers, life style, and stool characteristics? Participants will: Consume a standardized blue dye muffin after overnight fasting at the research center; Offer a finger prock blood samples for metabolic profiling; Collect stool samples for moisture measurement; Complete detailed questionnaires on diet, lifestyle, and bowel habits; Record the time of first blue stool appearance to determine GITT.
Eligibility Criteria
Inclusion Criteria: 1. 18-65 years old 2. 18.5 kg/m² ≤ BMI ≤ 25 kg/m² or BMI ≥ 30 kg/m² (people with normal weight or obesity) 3. Provision of informed consent to participate. Exclusion Criteria: 1. Gastrointestinal conditions which may affect nutrient absorption or gastric emptying, including coeliac disease, Crohn's disease, previous resection of the small intestine other than bariatric surgery, gastroparesis; 2. Using medications which effect gastric motility (e.g., domperidone, erythromycin, metoclopramide, prucalopride, opiates, loperamide, …) 3. The ingredients of blue muffins include gluten, nuts, baking powder, sugar, vanilla extract and sunflower oil. Participants with allergies to these ingredients; 4. Current diagnosis of cancer; 5. Advanced organ failure, including chronic kidney disease Stage 5, liver cirrhosis Child-Pugh B or C, intestinal failure, heart failure stage D, or chronic obstructive pulmonary disease stage 4; 6. Immobility; 7. Neuromuscular degenerative conditions associated with muscular atrophy, such as myasthenia gravis, muscular dystrophies, fibromyalgia, or multiple Sclerosis;
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07309250 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Gastrointestinal Transit Time. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07309250 currently recruiting?
Yes, NCT07309250 is actively recruiting participants. Contact the research team at christophe.matthys@uzleuven.be for enrollment information.
Where is the NCT07309250 trial being conducted?
This trial is being conducted at Leuven, Belgium.
Who is sponsoring the NCT07309250 clinical trial?
NCT07309250 is sponsored by KU Leuven. The trial plans to enroll 932 participants.