NCT07178509 A Study of SCAD Using Stress Contrast Echocardiography
| NCT ID | NCT07178509 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mayo Clinic |
| Condition | Spontaneous Coronary Artery Dissection |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-11-25 |
| Primary Completion | 2027-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2025-11-25 with a primary completion date of 2027-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.
Eligibility Criteria
Inclusion Criteria: * Adult \>18 years old * Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history Exclusion Criteria: * Unable to give consent * Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine. * Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®. * Pregnant. * Unable to interrupt breastfeeding. * Within 3 months of a heart attack. * Severe aortic stenosis. * Severe, uncontrolled hypertension (\>200/110 mmHg at baseline).
Contact & Investigator
Marysia Tweet, M.D., M.S.
PRINCIPAL INVESTIGATOR
Mayo Clinic
Frequently Asked Questions
Who can join the NCT07178509 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Spontaneous Coronary Artery Dissection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07178509 currently recruiting?
Yes, NCT07178509 is actively recruiting participants. Contact the research team at engrav.pamela@mayo.edu for enrollment information.
Where is the NCT07178509 trial being conducted?
This trial is being conducted at Rochester, United States.
Who is sponsoring the NCT07178509 clinical trial?
NCT07178509 is sponsored by Mayo Clinic. The principal investigator is Marysia Tweet, M.D., M.S. at Mayo Clinic. The trial plans to enroll 50 participants.