A Study of Pressure Waveform Analysis in Coronary Artery-II
Trial Parameters
Brief Summary
The goal of this observational study is to test the feasibility of intracoronary adenosine administration during coronary flow reserve(CFR) and index of microcirculatory resistance(IMR) assessment in a population with angina. The main questions it aims to answer are: * Repeatability of CFR and IMR assessment while hyperemia with intracoronary adenosine was administered. * Evaluate the correlation of the intrinsic signal of coronary waveform versus physiologic ischemia, while defined by fractional flow reserve(FFR) and CFR respectively. * The predictive value of FFR, CFR, and IMR on major adverse cardiovascular outcomes in 3 years Participants will undergo FFR, CFR, and IMR assessments in the catheterization laboratory of the National Taiwan University Hospital Hsin-Chu Branch, then clinical events follow up for 3 years.
Eligibility Criteria
Inclusion Criteria: * Participants with angina Exclusion Criteria: * Severe valvular heart disease * History of asthma * Heart rate less than 50 beats per minute * systolic blood pressure less than 90 mmHg