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Recruiting Phase 1, Phase 2 NCT06314373

A Study for HSK39775 in Participants With Solid Tumors

Trial Parameters

Condition Advanced Solid Tumors
Sponsor Xizang Haisco Pharmaceutical Co., Ltd
Study Type INTERVENTIONAL
Phase Phase 1, Phase 2
Enrollment 243
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-03-07
Completion 2028-02-01
Interventions
HSK39775 Monotherapy

Brief Summary

This research is designed to determine if HSK39775 is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

Eligibility Criteria

Inclusion Criteria: 1. Age 18 years or older at screening 2. Histological or cytological confirmation of advanced malignancy, have failed or intolerant to the standard-of-care treatment or no standard therapy is recognized or standard therapy is unavailable 3. Eastern Cooperative Oncology Group performance status 0 or 1 4. Patients must have evaluable disease as defined 5. Life expectancy of ≥ 12 weeks 6. Adequate organ and bone marrow function per protocol 7. Female patients who are women of childbearing potential with confirmed of a negative pregnancy test within 7 days prior to the first dose and agreement to the use of effective contraceptive method at the same time during study treatment period and for up to 6 months after the last dose of study treatment. Male patients must be willing to use effective contraception during the study treatment period and for up to 6 months after the last dose of study treatment 8. Written informed consent must be obtained Exclusion Criteria: 1. Kno

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