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Recruiting Phase 2 NCT07105488

NCT07105488 A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis

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Clinical Trial Summary
NCT ID NCT07105488
Status Recruiting
Phase Phase 2
Sponsor Bluefin Biomedicine, Inc.
Condition Atopic Dermatitis (AD)
Study Type INTERVENTIONAL
Enrollment 225 participants
Start Date 2025-07-15
Primary Completion 2027-02-28

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 75 Years
Study Type INTERVENTIONAL
Interventions
BFB759Placebo

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 225 participants in total. It began in 2025-07-15 with a primary completion date of 2027-02-28.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a double-blind, placebo-controlled study where subjects are participating for approximately 36 to 40 weeks. The study compares how well BFB759 works and how safe it is compared with a placebo.

Eligibility Criteria

Inclusion Criteria: * Are adults (18-75) with a diagnosis of atopic dermatitis for at least one year. * Have moderate to severe disease not adequately controlled by topical treatments. * Are willing to follow study instructions, attend regular visits, and avoid certain other medications during the study. Exclusion Criteria: * Have certain infections or other immune conditions. * Recently used medications that could interfere with the study. * Are pregnant or breastfeeding.

Contact & Investigator

Central Contact

Rob Eichelkraut

✉ Reichelkraut@bluefinbiomed.com

📞 +1-214-728-6505

Frequently Asked Questions

Who can join the NCT07105488 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Atopic Dermatitis (AD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07105488 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07105488 currently recruiting?

Yes, NCT07105488 is actively recruiting participants. Contact the research team at Reichelkraut@bluefinbiomed.com for enrollment information.

Where is the NCT07105488 trial being conducted?

This trial is being conducted at Phoenix, United States, Phoenix, United States, Encino, United States, Huntington Beach, United States and 11 additional locations.

Who is sponsoring the NCT07105488 clinical trial?

NCT07105488 is sponsored by Bluefin Biomedicine, Inc.. The trial plans to enroll 225 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology