NCT06290401 A Socio-ecological Approach for Improving Self-management in Adolescents With SCD
| NCT ID | NCT06290401 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Children's Hospital Medical Center, Cincinnati |
| Condition | Anemia, Sickle Cell |
| Study Type | INTERVENTIONAL |
| Enrollment | 310 participants |
| Start Date | 2025-02-03 |
| Primary Completion | 2028-01-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 310 participants in total. It began in 2025-02-03 with a primary completion date of 2028-01-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to evaluate the impact of SCThrive (a behavioral self-management intervention) on patient activation, self-management behaviors, daily functioning, and emergency room visits in 260 adolescents and young adults with sickle cell disease (SCD) ages 13-21 receiving care at 1 of 4 pediatric SCD clinics. The main question\[s\]it aims to answer are: * Does SCThrive improve patient activation? * Does SCThrive improve self-management behaviors, daily functioning, and decrease emergency room visits? * Are any improvements maintained 3 months after treatment? Participants will complete self-management related surveys before, after, and 3 months following their participation in an 8- week, virtual group intervention with an accompanying mobile app (SCThrive). Researchers will compare outcomes for participants who receive SCThrive and participants who receive uniform standard care (SCHealthED which = standard of care plus SCD educational text messages) to see if there are differences in patient activation, self-management behaviors, daily functioning, and emergency room visits.
Eligibility Criteria
Inclusion Criteria: * Patient of a participating SCD Clinic * Confirmed diagnosis of SCD * 13-21 years of age Exclusion Criteria: * Another chronic disease (which would complicate measurement of patient activation) * Non-English-speaking * Cognitive or psychiatric disorder that the physician or study therapists believe would impair study participation.
Contact & Investigator
Lori E. Crosby, PsyD
PRINCIPAL INVESTIGATOR
Children's Hospital Medical Center, Cincinnati
Frequently Asked Questions
Who can join the NCT06290401 clinical trial?
This trial is open to participants of all sexes, aged 13 Years or older, up to 21 Years, studying Anemia, Sickle Cell. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06290401 currently recruiting?
Yes, NCT06290401 is actively recruiting participants. Contact the research team at Ama.Wilson@cchmc.org for enrollment information.
Where is the NCT06290401 trial being conducted?
This trial is being conducted at Wilmington, United States, Atlanta, United States, Cincinnati, United States, Philadelphia, United States.
Who is sponsoring the NCT06290401 clinical trial?
NCT06290401 is sponsored by Children's Hospital Medical Center, Cincinnati. The principal investigator is Lori E. Crosby, PsyD at Children's Hospital Medical Center, Cincinnati. The trial plans to enroll 310 participants.
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