A Single Ascending Dose of HRS-2162 in Healthy Subjects
Trial Parameters
Brief Summary
The study is being conducted to evaluate the safety and tolerability of HRS-2162 injection in a single dose in healthy subjects, as well as the characteristics of PK/PD
Eligibility Criteria
Inclusion Criteria: 1. The subjects voluntarily signed the informed consent form. 2. Applicants must be between 18 and 45 years old at the time of signing the informed consent form, and both men and women are eligible . 3. ASA classification is Grade I (only Parts Two and three) 4. Male weight ≥50 kg, female weight ≥45 kg, body mass index between 19 and 28 kg/m ². 5. Adopt efficient contraceptive measures Exclusion Criteria: 1. Those with a past or current clinical acute or chronic disease 2. Those with a history of hereditary bleeding or coagulation disorders or non-traumatic bleeding . 3. Those with a history of neuromuscular diseases or poliomyelitis 4. Those with a history of anesthesia complications. 5. Those whose laboratory test results during the screening period or baseline period exceed the normal range and have clinical significance 6. The blood pressure of the subjects was abnormal and was judged by the researchers to be of clinical significance 7. The subject has a history