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Recruiting NCT07223151

NCT07223151 A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents

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Clinical Trial Summary
NCT ID NCT07223151
Status Recruiting
Phase
Sponsor Nana Gletsu Miller
Condition Obesity, Adolescent
Study Type INTERVENTIONAL
Enrollment 63 participants
Start Date 2025-07-25
Primary Completion 2027-06

Eligibility & Interventions

Sex All sexes
Min Age 12 Years
Max Age 18 Years
Study Type INTERVENTIONAL
Interventions
Unsweetened Sparkling Water ReplacementProgressively Reduced Sugar Beverage ReplacementPlain Water Replacement

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 63 participants in total. It began in 2025-07-25 with a primary completion date of 2027-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this clinical trial is to test whether replacing sugary sodas with unsweetened, flavored sparkling waters can reduce added sugar intake and improve health in Black/African American and Latine adolescents with obesity who prefer sweet-tasting beverages. The main questions it aims to answer are: * Does replacing sugary sodas with water change liking for sugary drinks, and water? * Do shifts in liking for sweetness lead to improved diet quality and cardiometabolic health? Researchers will compare replacing sugary sodas with one of three alternative beverages: unsweetened sparkling water, plain water, and beverages with gradually reduced sugar to determine which strategy is most effective. Participants will: * Replace sugary sodas with study drinks for 4 weeks * Complete taste tests to measure their liking for and sensory experience of sweetness over 8-weeks * Provide dietary recalls, body measurements, and blood samples over 8-weeks

Eligibility Criteria

Inclusion Criteria: * Adolescents ages 12 to 18 who display a "sweet-liker" pattern, characterized by a preference for higher concentrations of sugar in beverages, specifically identifying 0.3M (10.3% sucrose) or above as their most liked sample. * Have obesity (body mass index \[BMI\] \> 95%). During screening, subjects' height and weight will be measured to calculate BMI, and BMI will be balanced across study arms using stratified randomization. * Adolescents must also indicate a willingness to drink study beverages; not currently dieting/changing diet. Exclusion Criteria: * For the primary objective. Exclusion Criteria: * Adolescent participant is pregnant, since pregnancy affects taste perception * Participant is allergic or intolerant to the items we are testing. For the secondary objective. Exclusion Criteria: * Adolescent with type 1 or type 2 diabetes (self-declared or detected at screening visit through fasting glucose) * Currently consume unsweetened, sparkling water two or more times per week. * Adolescent participant is pregnant, since pregnancy affects taste perception * Participant is allergic or intolerant to the items we are testing. * Allergic or intolerant to the items that we are testing.

Contact & Investigator

Central Contact

Nana Gletsu Miller, PhD

✉ ngletsum@iu.edu

📞 +1 (812) 855-9110

Frequently Asked Questions

Who can join the NCT07223151 clinical trial?

This trial is open to participants of all sexes, aged 12 Years or older, up to 18 Years, studying Obesity, Adolescent. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07223151 currently recruiting?

Yes, NCT07223151 is actively recruiting participants. Contact the research team at ngletsum@iu.edu for enrollment information.

Where is the NCT07223151 trial being conducted?

This trial is being conducted at Bloomington, United States, Indianapolis, United States, West Lafayette, United States.

Who is sponsoring the NCT07223151 clinical trial?

NCT07223151 is sponsored by Nana Gletsu Miller. The trial plans to enroll 63 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology