NCT07437911 A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Supplement on Nutrient Gaps and Gut Health Among Individuals Utilizing GLP-1 RAs
| NCT ID | NCT07437911 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Athletic Greens International |
| Condition | Nutrition Intake |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2026-02 |
| Primary Completion | 2026-08 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 120 participants in total. It began in 2026-02 with a primary completion date of 2026-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is a triple-blind, placebo-controlled, randomized controlled trial of 120 adults that will evaluate the impact of a novel nutritional supplement on improving nutrient gaps and changing nutrient status and the gut microbiome among glucagon-like peptide-1 receptor agonist (GLP-1 RA) users.
Eligibility Criteria
Inclusion Criteria: * Be male or female * Be aged 18-59. * Has a BMI between 20-31.9. * Anyone currently taking GLP-1 medication at their maintenance dose (week 8+), and without any plans to alter their dosage. This includes: Semaglutide (Ozempic®, Wegovy®, Rybelsus®), Liraglutide (Saxenda®, Victoza®), Dulaglutide (Trulicity®), Exenatide (Byetta®, Bydureon®), Lixisenatide (Adlyxin®) * Anyone willing to follow the study protocol, including immediately prior to the all blood tests, duplicating their diet for 72 hours (3 days), refraining from caffeine and exercise for 24 hours, and fasting for 10 hours. * Anyone willing to maintain their current diet, sleep pattern, and activity levels for the duration of the trial. * Anyone willing to avoid introducing any other supplements, medications, or herbal remedies for the duration of this trial. * Anyone who is generally healthy - does not live with any diagnosed uncontrolled chronic disease. * Has access to a consistent weighing scale for the duration of the study. * Resides in the United States. Exclusion Criteria: * Anyone with a diagnosis of Type I or Type II diabetes. * Anyone with a diagnosis of any metabolic health condition, such as hypertension and dyslipidemia. * Anyone who has taken any multivitamin/multimineral supplements within the past 3 months. * Anyone who has taken a probiotic supplement within the past month. * Anyone who has regularly consumed (5 days/week or more) products that target healthy aging, anti-aging, longevity, gut health, energy, or ingestive behaviour (such as cravings), including resveratrol, quercetin, pterostilbene, coQ10, grapefruit, nicotinamide riboside, prebiotic fiber, green tea, niacin (vitamin B3) within the past 2 months. * Anyone who has received an antibiotic, antifungal, antiparasitic, or antiviral treatment within the past 90 days. * Anyone who has a known history of severe digestive disorders or metabolic conditions that impact nutrient absorption or metabolism, including acid reflux, Irritable Bowel Syndrome (IBS), Irritable Bowel Disease (IBD), Crohn's disease, a history of colon resection, gastroparesis, Inborn errors of metabolism (such as PKU), or gastrointestinal tract surgeries. * Anyone with any known allergies or hypersensitivities to any supplement product ingredients. * Anyone with any chronic health conditions that could impact participation in this study, such as asthma, gout, fibromyalgia, chronic inflammatory conditions (such as Crohn's, Lupus, HIV/AIDS), thyroid conditions, cancer (within the past 5 years), mental health disorders, history of serious illness in the last three months, history of substance abuse, or planned surgery during the study period. * Anyone currently pregnant, trying to conceive, or breastfeeding. * Anyone who has undergone a change in hormone therapy (including oral contraceptives) within the past 4 weeks, or is unwilling to maintain their current hormone therapy/oral contraceptive use throughout the course of the study. * Anyone who consumes more than 2 standard alcoholic drinks per day or more than 10 drinks per week, or has within the past 6 months. * Anyone who is currently a smoker or has been a smoker within the past month. * Anyone who follows a specific exclusion diet, including vegan, vegetarian, carnivore, paleo, atkins, or ketogenic.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07437911 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 59 Years, studying Nutrition Intake. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07437911 currently recruiting?
Yes, NCT07437911 is actively recruiting participants. Contact the research team at ellen@citruslabs.com for enrollment information.
Where is the NCT07437911 trial being conducted?
This trial is being conducted at Santa Monica, United States.
Who is sponsoring the NCT07437911 clinical trial?
NCT07437911 is sponsored by Athletic Greens International. The trial plans to enroll 120 participants.