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Recruiting Phase 1, Phase 2 NCT06718192

A Randomized Controlled Trial to Evaluate the Effectiveness of Bleomycin and Cryotherapy in Treating Plantar Warts.

Trial Parameters

Condition Verruca Plantaris
Sponsor The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Study Type INTERVENTIONAL
Phase Phase 1, Phase 2
Enrollment 70
Sex ALL
Min Age 18 Years
Max Age 65 Years
Start Date 2024-12-25
Completion 2025-06-30
Interventions
Bleomycin injectionCryotherapy

Brief Summary

To evaluate the efficacy of bleomycin and cryopreservation in the treatment of plantar verruca by dermoscopy and explore the influencing factors. Compare the safety, economic burden and impact on quality of life of the two treatments

Eligibility Criteria

Inclusion Criteria: Age 18-65 years old, gender is not limited; Consistent with the diagnosis of plantar warts; Volunteer for treatment and sign informed consent; Consent to photograph the lesion; The treatment target area can be selected (the target area must meet the following conditions: The distance between adjacent warts in the target area is \>0.5cm; The diameter of a single wart in the target area is ≤1.5cm, and/or the diameter of a wart mass is ≤1.5cm; The number of total warts/wart masses in the target area is ≤10). Exclusion Criteria: Patients who can't sign informed consent; Had previously received local treatment for common warts within 1 month; hiv-positive patient; Pregnant and lactating women; Has peripheral vascular disease; Allergic to bleomycin; People who are severely immunocompromised, or who are taking immunosuppressive drugs; Mental illness or cognitive incapacity; Other conditions deemed unsuitable for inclusion, such as inability to cooperate with follow-up, wer

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