NCT04538859 A Prospective Study of Factors Related to Exacerbation and Mortality of Non-cystic Fibrosis Bronchiectasis in Hong Kong
| NCT ID | NCT04538859 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chinese University of Hong Kong |
| Condition | Bronchiectasis Adult |
| Study Type | OBSERVATIONAL |
| Enrollment | 400 participants |
| Start Date | 2020-08-30 |
| Primary Completion | 2027-08-29 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 400 participants in total. It began in 2020-08-30 with a primary completion date of 2027-08-29.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Bronchiectasis is associated with repeated exacerbations which occurs at rates of 1.5-6.5 per patients per year, and are associated with an increased risk of admission and readmission to hospital, and high health care costs. In a local study carried out more than 10 years ago, idiopathic disease dominates and patients with bronchiectasis are mainly female with high hospitalization and mortality rates; 21.9 cases per 100,000 and 2.7 cases per 100,000 respectively. Moreover, exacerbation characterized by increases in symptoms requiring antibiotic treatment is associated with disease progression and significant mortality. Updated prevalence of this disease with the characteristics of etiology, clinical presentation and outcomes are needed to guide further management plan.
Eligibility Criteria
Inclusion Criteria: 1. Patients aged 18 years or older 2. Clinically stable for at least 4 weeks prior to enrollment (defined as no symptoms of exacerbation, no requirement for supplemental antibiotic therapy) 3. Diagnosis of bronchiectasis defined by high-resolution computed tomography scan Exclusion Criteria: 1. History of cystic fibrosis; hypogammaglobulinemia; allergic bronchopulmonary aspergilosis 2. Those who are unable to give consent
Frequently Asked Questions
Who can join the NCT04538859 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Bronchiectasis Adult. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04538859 currently recruiting?
Yes, NCT04538859 is actively recruiting participants. Visit ClinicalTrials.gov or contact Chinese University of Hong Kong to inquire about joining.
Where is the NCT04538859 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT04538859 clinical trial?
NCT04538859 is sponsored by Chinese University of Hong Kong. The trial plans to enroll 400 participants.